Abstract
Progress towards the development of alpha4beta2 nicotinic acetylcholinergic receptor pharmacophores is reviewed from the early Beers and Riech model to the newer vector models.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Drug Design
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Hydrogen Bonding
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Ligands
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Models, Chemical*
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Molecular Structure
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Nicotinic Agonists / pharmacology*
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Receptors, Nicotinic / drug effects*
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Receptors, Nicotinic / metabolism
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Structure-Activity Relationship
Substances
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Ligands
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Nicotinic Agonists
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Receptors, Nicotinic
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nicotinic receptor alpha4beta2